Savi

Dam

Conditions tested

273

MDR1 Drug Sensitivity

One copy

Everything else tested

No variant detected

Savi carries one copy of the MDR1 variant. MDR1 drug sensitivity is a recognized genetic risk in Australian Shepherd lines, and a dog with one copy is at increased risk of sensitivity to certain medications. About half of this litter will inherit one copy from Savi. Rico has none to pass on, so no puppy can inherit two.

Rico

Sire

Conditions tested

255

Progressive Retinal Atrophy, prcd

Carrier, one copy

Everything else tested

No variant detected

Rico is a PRA-prcd carrier. A carrier does not develop the condition. It takes two copies, one from each parent, and Savi tested clear. No puppy in this litter can be affected. About half will be carriers, which matters only if that dog is ever bred.

What the Litter Inherits

18 conditions relevant to this cross

MDR1 Drug Sensitivity

~50% one copy

Progressive Retinal Atrophy, prcd

~50% carrier, 0% affected

14 further breed-relevant conditions

All puppies clear

Hereditary Ataxia, Primary Ciliary Dyskinesia

No prediction returned

The 14 clear results include Degenerative Myelopathy, von Willebrand Disease Type I, Collie Eye Anomaly, Hereditary Cataracts, HUU, and Chondrodystrophy (CDDY/IVDD).

What Families Should Do About MDR1

Before any medication

A puppy's own MDR1 status is known only by testing that puppy. Until it is tested, treat any puppy from this pairing as possibly carrying one copy.

Share your dog's known or possible MDR1 status with your veterinarian whenever medications are being considered. That one conversation is the whole precaution. What MDR1 means.

Parent COI

Genomic, measured

Pairing eCOI

Calculated on this cross

Estimated litter eCOI

0%

Against the 15% ceiling

15 points under

Immune-gene diversity, Savi

No diversity

Immune-gene diversity, Rico

High diversity

A litter eCOI is not the average of the parents' figures. It is set by how much ancestry the two dogs share. Savi and Rico share almost none, so the expected figure for their puppies is 0% even though Savi herself measures 12%. Rico's high immune-gene (DLA) diversity offsets Savi's lack of it. Actual COI varies by puppy.

The Litter

Expected composition

• Miniature/MAS-type Australian Shepherd 50.0%
• Poodle 40.1%
• Bernese Mountain Dog 9.9%

Half shepherd, about 40% Poodle, under 10% Bernese. Expect a herding-breed mind and energy in a small, furnished doodle frame. This is not a mountain-dog build.

The Parents

Measured composition

Savi: Miniature/MAS-type Australian Shepherd

100.0%

Rico: Poodle (Small)

61.0%

Rico: Poodle (Standard)

19.3%

Rico: Bernese Mountain Dog

19.7%

Furnishings

RSPO2

Rico is FF, two furnishing copies. Savi is II, unfurnished. Every puppy receives one of each.

No unfurnished puppies are possible in this litter. Every puppy also carries one unfurnished copy from Savi, which matters only if that dog is ever bred.

Curl

KRT71

Rico is CT, wavy. Savi is CC, straight.

No puppy in this litter can be curly. Curl needs a T from each parent and Savi has none to give.

Shedding

MC5R

Rico is CT. Savi is CC. About half the litter will be CT and half CC.

MC5R has its clearest effect in unfurnished dogs. Every puppy here is furnished, and furnishings are the strongest coat-gene signal for lower shedding.

This litter should trend toward lower shedding across the board. The straight-coated half may shed somewhat more than the wavy half. No puppy is non-shedding, and individual coats are confirmed as each puppy develops.

What the Combinations Look Like

RSPO2 and KRT71 together

Because every puppy is furnished, the litter splits two ways rather than four.

Merle

M locus, PMEL

Savi is M*m, one merle allele. Rico is mm, no merle.

No double merle is possible. Only one parent carries merle. There is also no red in this litter to hide merle, so a merle puppy looks like one.

A standard genetic panel confirms that a merle allele is present but not its length, and length decides how strongly merle shows. We confirm each puppy's pattern as it develops.

Base Color

B locus, TYRP1

Savi is BB. Rico is bb, which is why he is a brown tri.

No brown puppies are possible, even though Rico is brown. Every puppy is black-based with a black nose, and every puppy carries one brown copy.

Pattern and Masking

E locus, K locus, A locus, D locus

E locus E^mE dam, EE sire

~50% masked

K locus kyky both parents

100% kyky

A locus atat both parents

100% tan points

D locus DD both parents

0% dilute

Every puppy is a tri: black or blue merle with tan points. No puppy can be red or apricot, and none are dilute. About half will carry a dark muzzle mask, which on a tri coat is often subtle.

White Spotting

S locus, MITF

Rico is Ssp, a parti carrier. Savi is SS, with no parti allele to give.

No parti puppies are possible in this litter. Parti needs sp from both parents. Expect tri coats with modest white on the chest, feet or muzzle. If you are waiting for a parti puppy, this is not your pairing.

What This Pairing Does Well

Strengths

• An expected litter COI of 0%, well under our 15% ceiling.
• Every puppy furnished. No smooth-faced puppies in this litter.
• A small dog, Petite to Mini, from a herding and Poodle cross.
• No double merle, no red, no brown, no dilute and no parti. Color comes down to black tri or blue merle tri.
• No puppy can be affected by any recessive condition on the panel.

What You Need to Weigh

Trade-offs, stated plainly

• About half will carry one MDR1 copy. Your veterinarian needs to know before prescribing.
• About half will be PRA-prcd carriers. Not affected, but relevant if ever bred.
• About half will be straight-coated, and none will be curly.
• Half shepherd. Expect a bright, busy herding mind that needs daily work.
• Savi measures 12% COI herself, the higher figure of the two parents.

Projection

From both parents' genomic weight predictions

Savi, dam

18 lb

Rico, sire

32 lb

Mid-parent

25 lb

Expected range

18 to 32 lb

Size class

Petite to Mini

Females

Tend toward the lower half

Males

Tend toward the upper half

Read This If You Wanted a Medium

Size honesty

The mid-parent figure sits on the line between Petite (16 to 25 lb) and Mini (26 to 35 lb). Adult weight is an estimate rather than a guarantee and may vary based on parentage, sex, generation, and individual development.

No puppy from this pairing is expected to reach Medium (36 to 50 lb). If you want a dog in that range, tell us and we will point you to a pairing planned for it.